David H. Price, PhD
Although I obtained a B.S. in Chemistry, I realized that I was more interested in the mechanisms of life. During my Ph.D. in Bill Marzluff's lab and postdoctoral stints at Caltech (Eric Davidson, Carl Parker) and Duke (Arno Greenleaf) I began to develop in vitro methods to study transcription and RNA processing. I started my lab at University of Iowa in 1989 and have worked since then to understand exactly how the elongation phase of transcription impacts eukaryotic gene expression. Discussing data and models with students and postdocs is my favorite pastime, but outside of lab I also enjoy the challenge of autocross.
After considering careers in music and mathematics, I settled on biology under the guidance of Dr. Dennis Miller at the University of Texas at Dallas, where I graduated in 2010. My classes and lab experiences got me interested in transcription and the regulation of gene expression. Fortunately, I ran into David during my interviews at Iowa and discovered that my textbooks never told the whole story. I am now working with him to further the plot, using HIV latency as a unique model for transcriptional understanding. When not learning to be a better scientist, I'm learning to be a better driver by autocrossing with David and John.
I "studied" biology and chemistry at Wayne State College in Nebraska, and graduated with a B.S. 2008. I was then recruited as a chemist for Cargill in Eddyville Iowa. It wasn't long before I knew that I needed a more academic outlet for my nerdiness. Serendipitously, I met my future boss during a local SCCA autocross event when I approached him about his so-called sponsor: P-TEFb. A discussion about transcriptional regulation ensued while standing on an airport runway littered with orange cones. In 2010 I was accepted to the University of Iowa Biochemistry department and am now exploring how P-TEFb is regulated through the 7SK snRNP.
Christine Lawson, BS
I am originally from the Mississippi Gulf Coast, and I received my BS in Biochemistry at Louisiana State University in 2014. With an interest in becoming a scientist, I began conducting research in a biochemistry lab at LSU. I also spent my summers exploring microbiology research (and big city living) in Richmond and NYC. After graduating, I moved to Iowa with my husband mid-winter. Coming from the deep south, I think I'm trapped in the Arctic. Not wanting to leave the lab, but not ready to pursue a graduate career, I joined the Price Lab to continue expanding the field of transcription regulation. When I’m not stuck in a block of ice, you can find me at the dog park with my German shepherd and my collie.
I am currently a third year undergraduate working towards a B. S. in biochemistry and a minor in chemistry. I am thrilled to be able to be a part of the action in the Price lab and work with these brilliant scientists. In the lab, Britt and John are letting me assist them with their research of 7SK. Outside the lab, you'll find me at games cheering on the Hawkeyes with my friends or having a game night with my crazy family.
I am originally from Omaha, Nebraska. I was initially drawn to the Price lab when, in our first meeting, David showed me how fascinating and rich the field of transcription is. I learned that there is a whole lot more to it than is taught in biochemistry class. My current project is an investigation of co-transcriptional RNA capping using radiolabeled in vitro transcription assays. In my free time I enjoy a good pickup soccer game or a night out with friends.